Abstract Single cell technologies allow the interrogation of tumor heterogeneity. providing insights into tumor evolution and treatment resistance. To better understand whether circulating tumor cells (CTCs) could complement metastatic biopsies for tumor genomic profiling. we characterized 11 single CTCs and 10 pooled CTC samples at the mutational and copy number aberration (CNA) levels. https://goodvibesbadhabiters.shop/product-category/curve-novelties/