Abstract Background Potent granulomatous inflammation responses induced by schistosome eggs and resultant fibrosis are the primary causes of morbidity in schistosomiasis. Recombinant Sj16 (rSj16). a 16-kDa protein of Schistosoma japonicum produced in Escherichia coli. has been demonstrated to have novel immunoregulatory effects in vivo and in vitro. https://www.parisnaturalfoodes.shop/product-category/vit-e-moist-creme/