Abstract CRISPR prime-editors are emergent tools for genome editing and offer a versatile alternative approach to HDR-based genome engineering or DNA base-editors. However. sufficient prime-editor expression levels and availability of optimized transfection protocols may affect editing efficiencies. especially in hard-to-transfect cells like hiPSC. https://thegreensjunglebeautyshops.shop/product-category/detangler/